words_blue_new.gif  NEW PRODUCT FOR API & PI       

**  Patent  **     Whole items in this list would be manufactured under non-infringible patent ship.

No.

Code    [ CLICK FOR SPEC. ]

Chemical Name

1

   CHPGA (CHMA)    

a-Cyclohexyl-a-phenylglycolic acid   or   a-Cyclohexyl Mandelic Acid   

2

CHPGA Methyl Ester

a-Cyclohexyl-a-phenyl glycolic acid Methyl ester    or

a-Cyclohexylmandelic acid Methyl ester

3

   Oxybutinin HCl     

 

4

   Azetidinone       

¡¡

5

   MPHP (TAA) 

4R-(4¡¯-Fluorophenyl)-3S-hydroxymethyl-1-benzylpiperidine    or

        Trans Amino alcohol   (TAA)

6

   CTAA                

   (-)-trans-4R-(4'-fluorophenyl)-3S-[(3',4'ethylenedioxyphenoxy)methyl]piperidine

7

   TSPH                  

t-Butyl 3R-tert-Butyldimethylsilyloxy-6-dimethoxyphosphinyl-5-oxohexanoate

  8

   CPMP

N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[4-(fluorophenyl)thio]-2-hydroxy-2-methylpropamide

9

   TCDH                  

tert-Butyl (3R,5S)-6-cyano-3,5-O-isopropylidene-3,5-dihydroxyhexanoate

10

   ABMB                 

 

11

   ATBA                  

 

12

   IMPA                  

 

13

   4-AA                   

 

14

   CCA                        

Chiral Chloro alcohol

15

Chiral Epoxide (CE) 

 

16

   DOMT

1-[2-(2,4-Difluorophenyl)Oxiranyl]Methyl-1H-1,2,4-Triazole

17

   IMPA   

 s-a-Isoprppyl-4-Methyl Phenyl Acetic Acid

18

   Atorvastatin Calcium

[R-(R*,R*0)-2(4-fluorophenyl)-beta,delta-dihydroxy-5-

(1-methylethyl)-3-phenyl-4[(phenylamino)carbonyl]-1H-pyrrole-

1-heptanoic acid, calcium salt(2:1) trihydrate

19

 

  Other Items under Development

 

   1)        Acyclovir

   2)        Alprazolam

   3)        Benazepril

   4)        Benidifine

   5)        Bupropion HCl

   6)        Buspiron HCl

   7)        Captopril

   8)        Cimetidine

   9)        Ciprofloxacin HCl

  10)      Fluvastatin

yellow08_up.gif go to top

1. CHPGA (CHMA)                                                                                         

 

   
 

1)    Chemical Name: a-Cyclohexyl-a-phenylglycolic acid   or     a-Cyclohexyl Mandelic Acid         

2)     Molecular Weight: 234.30       Formula : C14H18O3

3)     Specification          

       Chemical purity: min. 98.0%

       Appearance : White to off white crystalline powder   (Visual )

        Assay : Min. 98.0%                            (HPLC, Area %)

        Loss on Drying : Max. 1.0%                     (at 2 mmHg)

          Melting point : 149 ~ 150 °C               (Melting Point Apparatus/not revised)


4)     Application: Intermediate for Oxybutynin HCl

 

2. CHPGA Methyl Ester                                                                                   yellow08_up.gif go to top

   
 


1) Chemical Name

a-Cyclohexyl-a-phenyl glycolic acid Methyl ester    or   a-Cyclohexylmandelic acid Methyl ester

2) Specification

- Appearance                     Colorless to pale yellow viscous liquid

- Odor                                Characteristic

- Chemical purity     min. 98.0 %(GC area %)

- Loss of Drying       max. 0.5 %

- Water content       max. 0.1 %

- Boiling range         136 ~ 138 °C/ 2.0 mmHg (not revised)       


3. Oxybutinin HCl                                                                                            yellow08_up.gif go to top

 

                                          

1) Specification

Appearance : White Amorphous

Melting Point : 125 - 127 Deg C (STD. 124 - 129 Deg C)

Clarity: Complies  /        LOD : 0.03

Ignition Test : Residue not more than 1%.

Assay bynon-aqueous titration: 99.1% (STD>97.32 -101%)

Assay by HPLC: 99%    /     Heavy Metals: 0.002%

Molecular Formula: C22H32ClNO3    /      Merc Index No.: 7089

 

2) Application :  Anticholenargic

 

4. Azetidinone                                                                                              yellow08_up.gif go to top

-         Intermediate for Penem & Carbapenem Antibiotics

   
 


1) Chemical Name:  (3R,4R)-4-Acetoxy-3-[(R)-(tert-butyl-dimethylsilyloxy)-ethyl]-2-azetidinone

2) Molecular Weight: 287.4

3) Specification          Chemical purity: min. 97.0%

 Chiral purity: min. 97.0%


5. MPHP (TAA)                                                                                                  yellow08_up.gif go to top

-        Intermediate for Paroxetine HCl

   
  ¡¡

                                       

1) Chemical Name:

 Trans-(+-)-Methyl-4-fluorophenyl-3-hydroxymethyl piperidine

2) Molecular Weight: 223.29

3) Specification   Chemical purity: min. 97.0%

                            Chiral purity: min. 96.0%


6. CTAA                                                                                                  yellow08_up.gif go to top

-      The next step of TAA for antidepressant / Paroxetine HCl

 

   
 

1) Chemical Name:

 (-)-trans-4R-(4'-fluorophenyl)-3S-[(3',4'ethylenedioxyphenoxy)methyl]piperidine

2) Molecular Weight: 329.37

3) CAS No.: 61869-08-7

4) Brand Name: Paxil, Seroxat

5) Specification       Chemical purity: min. 97.0%

                    Chiral purity: min. 96.0%


7. TSPH                                                                                            yellow08_up.gif go to top

-        Intermediate for Cerivastatin, Fluvastatin & Rosuvastatin

                

 
¡¡


1) Chemical Name

                        t-Butyl 3R-tert-Butyldimethylsilyloxy-6-dimethoxyphosphinyl-5-oxohexanoate

2) Molecular Weight: 424.56

3) Specification             Chemical purity: min. 98.0%

                           Chiral purity: S-form, min. 99.0%


8. CPMP

                

 

1) Chemical Name

    N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-

    [4-(fluorophenyl)thio]-2-hydroxy-2-methylpropamide

2) Specification

    Appearance : white to off-white crystalline powder

    Assay : min. 99.00%

    Melting Point : 114 ~ 118¡É

    Water Content : max. 0.50%

                 Solubility : Soluble in Acetonitrile

 

9. TCDH                                                                                       yellow08_up.gif go to top

-         Intermediate for Atorvastatin

 

   
 

1) Chemical Name

          tert-Butyl (3R,5S)-6-cyano-3,5-O-isopropylidene-3,5-dihydroxyhexanoate

2) Molecular Weight: 269.34

3) Specification          Chemical purity: min. 97.0%

   Chiral purity: min. 96.0%


10. ABMB                                                                                               yellow08_up.gif go to top

 

11. ATBA    

 

12. IMPA                                                                                             yellow08_up.gif go to top

 

13. 4-AA